Treatment target re-classification of subjects comparing estimation of low-density lipoprotein cholesterol by the Friedewald equation and direct measurement of LDL-cholesterol
نویسندگان
چکیده
منابع مشابه
Measuring Low Density Lipoprotein Cholesterol: Comparison of Direct Measurement by HiSens Reagents and Friedewald Estimation
BACKGROUND Directly measured low density lipoprotein cholesterol (DLDLC) has been reported to be more accurate than calculated low density lipoprotein cholesterol (CLDLC) using the Friedewald equation. However, some limitations of DLDLC have been reported. In this study, we evaluated differences between CLDLC and DLDLC measured using HiSens reagents. METHODS Data were collected from 582 perso...
متن کاملEffect of serum lipoprotein(a) on estimation of low-density lipoprotein cholesterol by the Friedewald formula.
The calculation of serum low-density lipoprotein cholesterol (LDL-C) by the Friedewald formula does not account for the cholesterol associated with lipoprotein(a) [Lp(a)]. To quantify the contribution of Lp(a) cholesterol to total serum cholesterol, we measured concentrations of serum Lp(a) by an ELISA and concentrations of other serum lipids and lipoproteins by standard assays in 23 normolipem...
متن کاملComparison of friedewald formula and modified friedewald formula with direct homogeneous assay for low density lipoprotein cholesterol estimation.
OBJECTIVE To compare the Friedewald and modified Friedewald formulae with direct homogeneous assay for serum lowdensity lipoprotein cholesterol (LDL-C) levels estimation. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Armed Forces Institute of Pathology, Rawalpindi, from June to December 2011. METHODOLOGY Healthy subjects of either gender, from Rawalpindi, aged 18-75 year...
متن کاملDirect Measurement of LDL Cholesterol
able amounts of radiolabeled dextran in the plasma protein fraction [15]. Consequently, we do not think this mechanism plays a substantial role in producing the lower than expected dextran concentrations seen in the present study. The dextran we used had a mean molecular mass of 70 000 Da. Thus, some quantity of lower-molecular-mass dextran could have leaked out of the vascular space and distri...
متن کاملReactivity of direct assays for low-density lipoprotein (LDL) cholesterol toward charge-modified LDL in hypercholesterolemia.
BACKGROUND The aim of the present study was to compare 2 direct measurements for low-density lipoprotein cholesterol (LDL-C) with the Friedewald calculation (LDL-C [F]) in serum and their relationship with size-and charge-based LDL subfractions in serum ultracentrifugation fractions in patients with hypercholesterolemia (HC). METHODS AND RESULTS Serum samples from 283 HC patients who particip...
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ژورنال
عنوان ژورنال: Upsala Journal of Medical Sciences
سال: 2018
ISSN: 0300-9734,2000-1967
DOI: 10.1080/03009734.2018.1465496